Rockefeller University - Clinical Scholar, Laboratory of Molecular Immunology

“Antibody Feedback Regulation of Adaptive Immunity to Cognate Antigen”

Biological systems are often regulated through feedback loops. Dr. Schaefer-Babajew explores the issue of antibody feedback regulation on adaptive immune responses.

The impact of prevalent viral-specific Ab responses on nascent immune responses has been suggested, although mechanisms associated with this interplay are not identified. This proposed research provides an approach that can lead to a mechanism.

As most infections and vaccinations are serial in nature rather than a single exposure, this research is poised to have significant implications for our understanding of adaptive immunity against infections and for vaccine design.


About Dennis Schaefer-Babajew

Dr. Schaefer-Babajew received his M.D. from the Heidelberg University School of Medicine in Germany, where he was also awarded a doctorate in Immunology (Dr. med.) in 2019. In 2020, he started his postdoctoral studies at the Rockefeller University.

He has since transitioned to an instructor position in the Rockefeller University Clinical Scholars program, where he was named a Stavros Niarchos Foundation (SNF) Institute for Global Infectious Disease Research Clinical Scholar in 2023 and where he currently serves as one of the Chief Scholars.

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Siyuan Ding, Ph.D.